Protein Molecular Weight Markers
ABclonal Technology GABARAPL2 Rabbit pAb
Enables ubiquitin protein ligase binding activity. Involved in negative regulation of proteasomal protein catabolic process and protein localization to endoplasmic reticulum. Located in Golgi membrane and autophagosome membrane.
ABclonal Technology TMEM25 Rabbit pAb
Predicted to be involved in negative regulation of excitatory postsynaptic potential and regulation of protein stability. Predicted to be located in late endosome and lysosome.
Cayman Chemical CItrulntd Myeln BasIc Pr 500uL
An orally bioavailable broad-spectrum triazole antifungal agent completely inhibits growth of T. rubrum M. audouini M. canis and T. verrucosum as well as some C. albicans and A. fumigatus strains and other fungi (100 g/ml) bacteriostatic against E. coli P. aeruginosa S. aureus and S. pyogenes (100 g/ml) eliminates vaginal C. albicans candidiasis infection in 97 of rats (1 topical) eliminates vaginal C. albicans candidiasis infection in 50 of rats (10 mg/kg oral) decreases synthesis of 14a-desmethyl sterols and increases synthesis of methylated sterols in C. albicans (IC50 3 nM)
ABclonal Technology PPM1E Rabbit mAb
This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene.
ABclonal Technology FBXO42 Rabbit pAb
Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A, MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
ABclonal Technology IL17RA Rabbit pAb
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
ABclonal Technology BOLA3 Rabbit pAb
This gene encodes a protein that plays an essential role in the production of iron-sulfur (Fe-S) clusters for the normal maturation of lipoate-containing 2-oxoacid dehydrogenases, and for the assembly of the mitochondrial respiratory chain complexes. Mutation in this gene has been associated with multiple mitochondrial dysfunctions syndrome-2. Two alternatively spliced transcript variants encoding different isoforms with distinct subcellular localization have been reported for this gene (PMID21944046).
ABclonal Technology GUCY2F Rabbit pAb
The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa.
ABclonal Technology CACNA1D Rabbit pAb
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene.
Cayman Chemical VItelogenIncod PolycLNal 500uL
Isoprostanesprostaglandin PG-like productsof freeradicalinducedlipidperoxidation.{320 Although the isoprostanes derived from arachidonic acid are the best characterized many other polyunsaturated fatty acids can form isoprostanes.{7323} (±)5-iPF2a-VI is one of dozens of possible stereo- and regioisomeric isoprostanes which can be formed from arachidonic acid. To date the most extensively studied of these is 8-isoprostane (8-epi-PGF2a iPF2a-III).{30645011} However 8-isoprostane is a minor isoprostane constituent when compared to some of the other isomers which form in natural conditions of oxidative stress.{8367} (±)5-iPF2a-VI is an isoprostane from the unique Type VI class of isoprostanes. This class has been shown to be one of the major isoprostane products in contrast to 8-isoprostane. In addition to being produced in greater abundance than 8-isoprostane Type VI isoprostanes form internal lactones which facilitates their extraction purification fro biological samples8367940869106390
Biotang Inc Prestained Protein Marker (10-240 Kda),Three color bands(Green, Blue, Red). Ready-to-Use no need to boil.Broad range size estimation(11-240kDa). Highly purified and blended 11 recombinant proteins 2x250ul. Store at 2-8 deg.C
Prestained Protein Marker (10-240 Kda),Three color bands(Green, Blue, Red). Ready-to-Use no need to boil.Broad range size estimation(11-240kDa). Highly purified and blended 11 recombinant proteins 2x250ul. Store at 2-8 deg.C
![ABclonal Technology [KO Validated] PRKAR1A Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000138662.jpg-250.jpg)
ABclonal Technology [KO Validated] PRKAR1A Rabbit pAb
cAMP is a signaling molecule that activates cAMP-dependent protein kinase, which transduces signals through phosphorylation of target proteins. The inactive kinase is a tetramer of two regulatory and two catalytic subunits. cAMP dissociates this holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free catalytic subunits. This gene encodes one of the regulatory subunits and was found to down-regulate liver gene expression in hepatoma-fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). The gene can fuse with the RET protooncogene to form the PTC2 chimeric oncogene in thyroid tumors. A nonconventional nuclear localization sequence suggests its role in DNA replication by transporting the RFC40 subunit. Several splice variants encoding different isoforms have been observed.
Biolegend Purified anti-mouse Podoplanin
Purified anti-mouse Podoplanin Recombinant [QA20A17]; Isotype: Rat IgG1, κ; Reactivity: Mouse; Apps: FC; Size: 100 μg
Hach Company 5500sc Standard 2 Low-Range Phosphate standard solution, 2 L - for 5500sc low-range phosphate analyzer
Standard 2 low-range phosphate calibration solution in a 2 L bottle for use with the Hach 5500sc low-range phosphate analyzer. Use this certified standard to perform calibration and routine accuracy checks to help ensure reliable phosphate measurements.
- Provides a low-range phosphate calibration standard for analyzer verification.
- Packaged in a 2 L bottle for extended use and fewer changeovers.
- Supports routine accuracy checks and instrument performance verification.
- Ready-to-use formulation for convenient calibration procedures.
